Postdoctoral Scholar - Molecular and Precision Medicine
Job Description
APPLICATION INSTRUCTIONS:
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CURRENT PENN STATE STUDENT (not employed previously at the university) and seeking employment with Penn State, please login to Workday to complete the student application process. Please do not apply here, apply internally through Workday.
If you are NOT a current employee or student, please click “Apply” and complete the application process for external applicants.
Approval of remote and hybrid work is not guaranteed regardless of work location. For additional information on remote work at Penn State, see Notice to Out of State Applicants.
This is a term position; length of the term will be discussed during the interview process. Continuation past the term length discussed will be based on university need, performance, and/or availability of funding.
POSITION SPECIFICS
The Grigoryev Lab at the Penn State College of Medicine, Department of Molecular and Precision Medicine in Hershey, Pennsylvania is seeking an entry level postdoctoral scholar with extensive hands-on experience with Cryo-Electron Tomography (Cryo-ET), including sample preparation (vitrification), data collection, and tomogram reconstruction.
Qualifications:
Applicants must have a doctoral degree in Biomedical Sciences, Structural Biology, Biochemistry, Molecular Biology, Biophysics, or a related field.
The successful candidate must demonstrate experience in the structural and biochemical analysis of chromatin, including techniques such as: Chromatin fractionation using methods like differential solubility or ultracentrifugation, in vitro reconstitution of nucleosome arrays from DNA templates and histones, proficiency in standard molecular biology and biochemical techniques, experience with 3D image processing and modeling software for structural analysis (such as IMOD and UCSF Chimera).
A strong background in computational biology and bioinformatics, with experience in: Applying deep-learning or AI-based methods for image denoising. analysis of whole-genome sequencing (WGS) or other large-scale sequencing data, utilizing bioinformatics tools and databases (e.g., ENCODE, UCSC genomic database) for epigenomic analysis is required.
Proficiency in mammalian cell culture techniques, including experience with both adherent (e.g., HeLa, NIH/3T3) and suspension (e.g., K562) cell lines is preferred.
A current CV and cover letter must be submitted when applying for this position.
BACKGROUND CHECKS/CLEARANCES
Employment with the University will require successful completion of background check(s) in accordance with University policies.
BENEFITS
Penn State provides a competitive benefits package for full-time employees designed to support both personal and professional well-being.
For more detailed information, please visit our Benefits Page.
CAMPUS SECURITY CRIME STATISTICS
Pursuant to the Jeanne Clery Disclosure of Campus Security Policy and Campus Crime Statistics Act and the Pennsylvania Act of 1988, Penn State publishes a combined Annual Security and Annual Fire Safety Report (ASR). The ASR includes crime statistics and institutional policies concerning campus security, such as those concerning alcohol and drug use, crime prevention, the reporting of crimes, sexual assault, and other matters. The ASR is available for review here.
EEO IS THE LAW
Penn State is an equal opportunity employer and is committed to providing employment opportunities to all qualified applicants without regard to race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. If you are unable to use our online application process due to an impairment or disability, please contact 814-865-1473.
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